Dr Saw Seow Hoon organized a poster competition in Next-Generation Sequencing (NGS) for Infectious Disease Diagnosis and Management workshop at UTAR Kampar campus. This workshop aims to discuss the utilization of bioinformatics tools and NGS in infectious diseases with Year 3 Biomedical students.
Next-generation sequencing (NGS) technologies are increasingly being used for diagnosis and monitoring of infectious diseases. Thus, the students are required to review ONE application of NGS, including the utilisation of related bioinformatics tools in clinical microbiology, focusing on genotypic resistance testing, direct detection of unknown disease-associated pathogens in clinical specimens, investigation of microbial population diversity in the human host, and strain typing. The students are required to organize the review into one of these applications: i) applications in clinical virology, ii) applications in clinical bacteriology, mycobacteriology, and mycology, and iii) validation, quality control, and maintenance of proficiency. Although NGS holds enormous promise for clinical infectious disease testing, many challenges remain, including automation, standardizing technical protocols and bioinformatics pipelines, improving reference databases, establishing proficiency testing and quality control measures, and reducing cost and turnaround time, all of which would be necessary for widespread adoption of NGS in clinical microbiology laboratories.
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